hrp0086p1-p563 | Perinatal Endocrinology P1 | ESPE2016

Hyponatremia in Infants Under 100 Days Old: Frequently Overlooked and Multifactorial

Storey Caroline , Dauger Stephane , Baud Olivier , Deschenes Georges , Carel Jean-Claude , Martinerie Laetitia

Background: Hyponatremia is one of the most common electrolyte disorders in hospitalized children and early diagnosis and management are crucial to prevent morbidity and mortality. Because of the physiological resistance to aldosterone under 3 months of age, the mechanisms leading to hyponatremia are often misunderstood.Objective and hypotheses: To assess the prevalence of hyponatremia in hospitalized infants younger than 100 days and evaluate the mechan...

hrp0086p1-p569 | Perinatal Endocrinology P1 | ESPE2016

Maternal Nutritional Risk Factors Associated with Neonatal Hyperinsulinism

Louvigne Mathilde , Rouleau Stephanie , Bouhours-Nouet Natacha , Donzeau Aurelie , Caldagues Emmanuelle , Souto Isabelle , Montcho Yannis , Bouvagnet Audrey Migraine , Baud Olivier , Leger Juliane , Carel Jean-Claude , Gascoin Geraldine , Coutant Regis

Background: Neonatal hyperinsulinism is the most frequent cause of neonatal recurrent hypoglycaemia. The persistent form can be explained by mutations of genes involved in beta cell function, whereas the transient form can occur in case of prematurity, low birth weight, macrosomia, perinatal hypoxia, and maternal diabetes.Objective and hypotheses: As we observed an increase in the incidence of neonatal hyperinsulinism, we hypothesized that potential mate...